A DEFICIENCY OF APOPTOSIS INDUCING FACTOR (AIF) IN HARLEQUIN MOUSE HEART MITOCHONDRIA PARADOXICALLY REDUCES ROS GENERATION DURING ISCHEMIA-REPERFUSION

Background and Aims: AIF (apoptosis inducing factor) is a flavin and NADH containing protein located within mitochondria required for optimal function of the respiratory chain.AIF may function as an antioxidant within mitochondria, yet when released from mitochondria it activates caspase-independent cell death.The Harlequin (Hq) mouse has a markedl

Mobile edge computing (MEC) has attracted extensive studies recently due to its ability to augment the computational capabilities of mobile devices.This paper considers a cache-enhanced multiuser MEC system where the task can be cached in the MEC servers to avoid the transmission of duplicate data.To further improve the energy efficiency and satisf

Replication is a fundamental aspect of cancer, and replication is about reproducing all the elements and structures that form a cell.Among them are DNA, RNA, enzymes, and coenzymes.All the DNA is doubled during each S C-500 (synthesis) cell cycle phase.This means that six billion nucleic acids must be synthesized in each cycle.Tumor growth, prolife

Human dexterity is an invaluable capability for precise manipulation of objects in complex tasks.The capability of robots to similarly grasp and perform in-hand manipulation of objects is critical for their use in the ever changing human environment, and for their ability to replace manpower.In recent decades, significant effort has been put in ord

In East Asia, satellite observation is important because aerosols from natural and anthropogenic sources have been recognized Sequin Shirt as a major source of regional and global air pollution.However, retrieving aerosols properties from satellite observations over land can be difficult because of the surface reflection, complex aerosol compositio